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LAG-1 Recombinant Protein

Basic information

Name

LAG-1 Recombinant Protein

size

0.005 mg, 0.02 mg

Catalog number

40-406

Price

683 €

Details and extended information

NCBI ID

6351

Protein's origin

Human

Uniprot

P13236

Recombinant in

E. coli

Rec. PROTEIN GI#

4506845

Vial

Lyophilized

Accession nr

NP_002975.1

Group

recombinants

Source

Homo sapiens

Additional source

Recombinants or rec. proteins

Gene name

chemokine (C-C motif) ligand 4

About

This product is for research use only.

SEQUENCE

APMGSDPPTA CCFSYTARKL PRNFVVDYYE TSSLCSQPAV VFQTKRSKQV CADPSESWVQ EYVYDLELN

Pureity

Greater than 98% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg).

Activity

Biological activity was determined by it's ability to chemoattract CCR5 transfected cells using a concentration of 0.1 - 10.0 ng/mL

Other name of the recombinant

ACT2, G-26, HC21, LAG1, LAG-1, MIP1B, SCYA2, SCYA4, MIP1B1, AT744.1, MIP-1-beta, C-C motif chemokine 4, G-26 T-lymphocyte-secreted protein

About recombinant protein

LAG-1 is CC chemokine that signals through the CCR5 receptor. LAG-1 is identical to MIP-1beta (ACT II isotype) except for two amino acid substitutions; arginine for histidine at position 22 and serine for glycine at position 47 of the mature protein. LAG-1 chemoattracts monocytes, and exhibits activity as an HIV suppressive factor. Recombinant human LAG-1 is a 7.7 kDa protein containing 69 amino acid residues.

Keep at

The lyophilized LAG-1 recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted LAG-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing LAG-1 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.