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anti-CCL4 Antibody

Basic information

Name

anti-CCL4 Antibody

size

0.02 mg, 0.1 mg

Catalog number

7227

Price

180 €

Details and extended information

Immunoglobulin

IgG

GENE symbol

CCL4

NCBI GENE nr

6351

Ab raised in

Rabbit

Protein nr

P13236

Omim nr

4506845

Quantity per ml

1 mg/mL

Ncbi nr

NP_002975

French translation

anticorps

Type

Polyclonal

Vial with antibody

in solution

Source

homo sapiens

Antibodie's label

unlabelled serum

KDa

Predicted: 10 kDa

Works with

Human, Mouse, Rat

Antigene name

chemokine (C-C motif) ligand 4

Suspention, pH, azide

CCL4 Antibody is supplied in PBS containing 0.02% sodium azide.

Immuno application

ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence

Purity

CCL4 Antibody is affinity chromatography purified via peptide column.

Antibody advice

CCL4 antibody can be used for detection of CCL4 by Western blot at 1 - 2 ug/mL.

Antigen

Rabbit polyclonal CCL4 antibody was made against a 15 amino acid peptide near the center of human CCL4.

Keep at

CCL4 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year.

Properties

If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Gene names

CCL4 Antibody: ACT2, G-26, HC21, LAG1, LAG-1, MIP1B, SCYA2, SCYA4, MIP1B1, AT744.1, MIP-1-beta, C-C motif chemokine 4, G-26 T-lymphocyte-secreted protein

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Gene info

CCL4 Antibody: CCL4, also known as macrophage inflammatory protein 1-beta (MIP1B), belongs to the intercrine beta (chemokine CC) family. Both CCL4 and the related protein CCL3 participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells. While both CCL4 and CCL3 exert similar effects on monocytes, their effect on lymphocytes differ; with CCL4 selectively attracting CD4+ lymphocytes and CCL3 selectively attracting CD8+ lymphocytes. Additionally, both have been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. The processed form of CCL4 can induce down-modulation of surface expression of the chemokine receptor CCR5, thus inhibiting the CCR5-mediated entry of HIV-1 in T cells.