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CCL4/MIP1 beta Antibody

Basic information

Name

CCL4/MIP1 beta Antibody

size

0,1 mg

Catalog number

PB9572

Price

374 €

Details and extended information

Entrez GeneID

6351

Gene Name

CCL4

Raised in

rabbit

Uniprot ID

P13236

Analyses

WB,ELISA

French translation

anticorps

Product form

freeze-dried

Target antigen

CCL4/MIP1 beta

Reacts with species:

human, mouse, rat

Clonality

Polyclonal antibody

Clone

Polyclonal antibody

Protein Name

C-C motif chemokine 4

Type of the antibody

IgG polyclonal antibody

Purification

Immunogen affinity purified.

Gene Full Name

chemokine (C-C motif) ligand 4

Product configuration

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Solubilization

The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml

Properties

If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Immunogen

E. coli-derived human CCL4 recombinant protein (Position: A24-N92). Human CCL4 shares 76.8% and 79.7% amino acid (aa) sequence identity with mouse and rat CCL4, respectively.

Tips

The CCL4/MIP1 beta Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.

Storage condtions

Keep the CCL4/MIP1 beta Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.

Related articles

1. Bystry RS, Aluvihare V, Welch KA, Kallikourdis M, Betz AG (December 2001). "B cells and professional APCs recruit regulatory T cells via CCL4". Nat. Immunol. 2 (12): 1126–32. 2. Cocchi F, DeVico AL, Garzino-Demo A, Arya SK, Gallo RC, Lusso P (December 1995). Science (journal) 270 (5243): 1811–5. 3. Irving SG, Zipfel PF, Balke J, McBride OW, Morton CC, Burd PR, Siebenlist U, Kelly K (June 1990). Nucleic Acids Res. 18 (11): 3261–70. 4. Kamin-Lewis R, Abdelwahab SF, Trang C, Baker A, DeVico AL, Gallo RC, Lewis GK (July 2001).

Background

Chemokine(C-C motif) ligand 4, also known as CCL4, is a protein which in human is encoded by the CCL4 gene. By analysis of somatic cell hybrids and by in situ hybridization, the CCL4 gene was assigned to 17q21-q23. It is a CC chemokine with specificity for CCR5 receptors. And it is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. CCL4 is a major HIV-suppressive factor produced by CD8+ T cells. Performing-low memory CD8+ T cells that normally synthesize CCL4. Based on functional analysis of CCL4, one or more additional beta chemokine receptors that transduce CCL4 signals must also exist. MIP-1alpha and CCL4 have been shown to lack affinity for the erythrocyte surface chemokine receptor/Duffy antigen that binds many alpha as well as beta chemokines(11, 14).

Synonyms

MIP 1 beta antibody|Secreted protein G 26 antibody|ACT 2 antibody|ACT-2 antibody|ACT2 antibody|AT744.1 antibody|AT744.2 antibody|C C motif chemokine 4 antibody|C C motif chemokine 4 like antibody|CC chemokine ligand 4 antibody|CC chemokine ligand 4L1d2 antibody|CC chemokine ligand 4L2 antibody|CCL4 antibody|CCL4_HUMAN antibody|ccl4l 1 antibody|CCL4L antibody|CCL4L1 antibody|Chemokine (C C motif) ligand 4 antibody|Chemokine (C C motif) ligand 4 like 1 antibody|Chemokine (C C motif) ligand 4 like 1, telomeric antibody|Chemokine (C C motif) ligand 4 like 2 antibody|Chemokine CC Motif Ligand 4 antibody|G 26 antibody|G 26 T lymphocyte secreted protein antibody|G-26 T-lymphocyte-secreted protein antibody|HC21 antibody|LAG 1 antibody|LAG-1 antibody|LAG1 antibody|Lymphocyte activation gene 1 antibody|Lymphocyte activation gene 1 protein antibody| Macrophage inflammatory protein 1 beta antibody|Macrophage inflammatory protein 1-beta antibody|Macrophage inflammatory protein 1b2 antibody|MGC104418 antibody|MGC126025 antibody|MGC126026 antibody|MIP-1-beta antibody|MIP-1-beta(1-69) antibody|MIP-1-beta(3-69) antibody|MIP1 beta antibody|MIP1B antibody|MIP1B1 antibody|Monocyte adherence induced protein 5 alpha antibody|PAT 744 antibody|Protein H400 antibody|SCYA2 antibody|SCYA4 antibody|SCYA4L antibody|Secreted protein G26 antibody|SIS gamma antibody|SIS-gamma antibody|Small inducible cytokine A4 (homologous to mouse Mip 1b) antibody|Small inducible cytokine A4 antibody|Small-inducible cytokine A4 antibody|T cell activation protein 2 antibody|T-cell activation protein 2 antibody