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CCL3 Antibody

Basic information

Name

CCL3 Antibody

size

0,1 mg

Catalog number

PB9571

Price

374 €

Details and extended information

Target antigen

CCL3

Entrez GeneID

6348

Gene Name

CCL3

Raised in

rabbit

Uniprot ID

P10147

Analyses

WB,ELISA

French translation

anticorps

Product form

freeze-dried

Reacts with species:

human, mouse, rat

Clone

Polyclonal antibody

Clonality

Polyclonal antibody

Protein Name

C-C motif chemokine 3

Type of the antibody

IgG polyclonal antibody

Purification

Immunogen affinity purified.

Gene Full Name

chemokine (C-C motif) ligand 3

Product configuration

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Solubilization

The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml

Properties

If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Immunogen

E. coli-derived human CCL3 recombinant protein (Position: S24-A92). Human CCL3 shares 75.8% and 77.3% amino acid (aa) sequence identity with mouse and rat CCL3, respectively.

Tips

The CCL3 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.

Storage condtions

Keep the CCL3 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.

Background

Macrophage inflammatory protein-1 alpha (MIP-1 alpha), also called CCL3, LD78. The cDNA for CCL3 predicts a mature peptide of 69 amino acids with a molecular mass of 7,889 daltons. CCL3 is a member of a newly identified superfamily of small inducible proteins involved in inflammatory responses, wound healing and tumorigenesis. CCL3 is a chemokine that has pro-inflammatory and stem cell inhibitory activities in vitro. It constitutes an important second signal for mast cell degranulation in the conjunctiva in vivo and consequently for acute-phase disease.

Related articles

1. Cook, D. N.; Beck, M. A.; Coffman, T. M.; Kirby, S. L.; Sheridan, J. F.; Pragnell, I. B.; Smithies, O. Requirement of MIP-1-alpha for an inflammatory response to viral infection. Science 269: 1583-1585, 1995. 2. Miyazaki, D.; Nakamura, T.; Toda, M.; Cheung-Chau, K.-W.; Richardson, R. M.; Ono, S. J. Macrophage inflammatory protein-1-alpha as a costimulatory signal for mast cell-mediated immediate hypersensitivity reactions. J. Clin. Invest. 115: 434-442, 2005. 3. Nakao, M.; Nomiyama, H.; Shimada, K. Structures of human genes coding for cytokine LD78 and their expression. Molec. Cell. Biol. 10: 3646-3658, 1990. 4. Wolpe, S. D.; Cerami, A. Macrophage inflammatory proteins 1 and 2: members of a novel superfamily of cytokines. FASEB J. 3: 2565-2573, 1989.

Synonyms

C C motif chemokine 3 antibody|CCL 3 antibody|CCL3 antibody|CCL3_HUMAN antibody|Chemokine C|C motif ligand 3 antibody|Chemokine CC Motif Ligand 3 antibody|G0/G1 switch regulatory protein 19 1 antibody|G0/G1 switch regulatory protein 19-1 antibody|G0S19 1 antibody| G0S19 1 protein antibody|Heparin binding chemotaxis protein antibody|L2G25B antibody|LD78 alpha antibody|LD78-alpha(4-69) antibody| LD78ALPHA antibody|Macrophage inflammatory protein 1 alpha antibody|Macrophage inflammatory protein 1-alpha antibody|MIP 1 alpha antibody|MIP 1A antibody|MIP-1-alpha antibody|MIP-1-alpha(4-69) antibody|MIP1A antibody|PAT 464.1 antibody|SCYA 3 antibody|SCYA3 antibody|SIS alpha antibody|SIS beta antibody|SIS-beta antibody|Small inducible cytokine A3 antibody|Small-inducible cytokine A3 antibody|Tonsillar lymphocyte LD78 alpha protein antibody